ABSTRACT
Background: Birth is often referred to as “the miracle of life” and very rightly so since successful pregnancy represents a complex, a highly coordinated succession of biological processes. In this regard, it is remarkable that pregnancy ever occurs at all. Infertility is a reproductive system disorder affecting 10.7% to 15.5% of couples. Highly heterogeneous in etiology. Investigating the cause is necessary for guiding treatment options. Aim of the study was to determine the percentage of immature oocytes retrieved at the metaphase 1 stage and germinal vesicle stage and its outcome.Methods: Total 30 cases were included for this retrospective analysis of data done at ARC fertility center, Saveetha Medical College. This study analyzed the data of patients with unexplained infertility who underwent ICSI centers (affiliated to Saveetha University) meeting inclusion criteria and willing to participate in the study.Results: The mean number of fertilized oocytes among those with more than 25% immature oocyte proportion was 1.18 while among those with less than 25% immature oocyte proportion was 4.13. The chance of fertilization of the oocyte increases when the percentage of immature oocyte was less than or equal to 25%. The association was found to be statistically significant with p-value <0.05.Conclusions: Thus, some intrinsic oocyte factor could be involved in causing maturation arrest in such couples and resulting in multiple failed IVF cycles.so this oocyte factor could be a major cause in many cases of unexplained infertility.
ABSTRACT
Background: The study aimed to analyse the trends in the growth pattern of the children in the age group of 3-21 years of both boys and girls using body mass index (BMI). The study also compared the BMI of the sample with the WHO norms and the group average.Methods: A study was conducted in India covering 1728 children 849 boys and 879 girls from LKG grade to +2 grades in the age group of 3-21 years. BMI grades were computed as per WHO 2006 standards (underweight- <18.50, normal- 18.50-24.99, overweight- >25.00 and obese- >30.00). Results were analyzed using percentage and ANOVA.Results: The data shows that 88.9% of children in the age group of 3-8 years are underweight and in 15-21 years of age children are relatively healthy, but are inclined to move to overweight (17.66%) and obesity (7.21%). More of boys (31%) tend to be underweight than girls. Age and gender were found to be significantly related to BMI. The average BMI of the sample group is above the national standards of WHO (World Health Organization) in all the three age groups. Boys are found to be on par with WHO norms while girls exceed the same. Majority of the sample were below the average denoting underweight.Conclusions: Age and gender was significantly related with BMI. Average BMI of the sample was on par with national standard of WHO. BMI was thus found to be an effective tool for predicting the well-being of school children.